牛布氏杆菌感染小鼠和大鼠的易感性。
THE SUSCEPTIBILITY OF MICE AND RATS TO INFECTION WITH BACILLUS ABORTUS.
机构信息
Department of Animal Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
出版信息
J Exp Med. 1922 Nov 30;36(6):727-33. doi: 10.1084/jem.36.6.727.
Abstract
- White mice are highly susceptible to infection by inoculation with Bacillus abortus. The susceptibility appears to be as great as that of the guinea pig, and this animal probably can be substituted satisfactorily for guinea pigs in diagnostic work. 2. Both mice and rats are very refractory to feeding infection with Bacillus aborlus. The failure to infect mice in this way was complete, but the feeding of large amounts of culture gave infection in rats. Subcutaneous inoculation resulted in infection of all the animals. The difficulty of infecting rats and mice with Bacillus abortus by feeding makes it very doubtful whether these animals can have any rôle in the propagation and spread of infectious abortion in cattle.
摘要
白色老鼠极易通过接种牛流产布氏杆菌而感染。其易感性似乎与豚鼠一样大，因此这种动物很可能可以满意地替代豚鼠用于诊断工作。
老鼠和大鼠都非常不容易通过喂食感染牛流产布氏杆菌。以这种方式感染老鼠是完全失败的，但喂食大量培养物会使大鼠感染。皮下接种导致所有动物感染。通过喂食感染牛流产布氏杆菌的大鼠和小鼠非常困难，这使得这些动物在牛传染性流产的传播和蔓延中是否有任何作用非常值得怀疑。
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