甲状腺细胞的纯系及其特性。
A PURE STRAIN OF THYROID CELLS AND ITS CHARACTERISTICS.
机构信息
Laboratories of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1925 Feb 28;41(3):337-46. doi: 10.1084/jem.41.3.337.
Abstract
- A pure strain of thyroid epithelium was isolated and maintained in active condition for 7 months. At the end of the experiment, the rate of cell multiplication was as great as at its beginning. 2. The thyroid cells grew at the surface of the coagulum as pavement epithelium, and within the coagulum as a glandular structure. 3. The cells did not dedifferentiate, and the lumen of the acini in cultures from a strain over 4 months old contained colloid secretion similar morphologically to that from a freshly extirpated thyroid gland.
摘要
甲状腺上皮的纯培养物被分离出来，并在活跃状态下维持了 7 个月。实验结束时，细胞增殖率与开始时一样高。
甲状腺细胞在凝块表面作为铺石上皮生长，在凝块内部作为腺结构生长。
细胞没有去分化，而且来自培养超过 4 个月的一株的滤泡腔中含有胶体分泌物，在形态上与刚切除的甲状腺相似。
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