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过敏性休克与结核杆菌的部分抗原。

ANAPHYLACTIC SHOCK WITH THE PARTIAL ANTIGEN OF THE TUBERCLE BACILLUS.

机构信息

Department of Bacteriology and Immunology, Harvard University Medical School, Boston.

出版信息

J Exp Med. 1929 Nov 30;50(6):777-86. doi: 10.1084/jem.50.6.777.

Abstract
  1. Typical lethal anaphylactic shock has been produced in guinea pigs by means of the specific carbohydrate derived from a human strain of tubercle bacillus. The phenomenon has been observed in animals both actively and passively sensitized. 2. Typical contractions have been evoked in the isolated uterus of guinea pigs upon the addition of the specific carbohydrate to the bath. 3. True anaphylactic shock against the specific carbohydrate in guinea pigs sensitized with the tubercle bacillus does not prevent or diminish the cutaneous reaction to O. T. in those animals which recover.
摘要
  1. 通过从一株人类结核分枝杆菌中提取的特定碳水化合物,豚鼠发生了典型的致死性过敏性休克。该现象在主动和被动致敏的动物中都观察到了。

  2. 向浴槽中加入特定碳水化合物,可诱发豚鼠离体子宫产生典型收缩。

  3. 用结核分枝杆菌致敏的豚鼠对该特定碳水化合物发生的真正过敏性休克,并不能阻止或减轻那些恢复动物对 O.T.的皮肤反应。

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本文引用的文献

1
ANAPHYLAXIS WITH THE TYPE-SPECIFIC CARBOHYDRATES OF PNEUMOCOCCUS.
J Exp Med. 1929 Jan 31;49(2):251-66. doi: 10.1084/jem.49.2.251.
2
ON THE ROLE OF CARBOHYDRATE HAPTENS IN BACTERIAL ANAPHYLAXIS.
J Exp Med. 1928 Feb 29;47(3):379-88. doi: 10.1084/jem.47.3.379.

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