在狗身上实验性诱发与白细胞减少症及骨髓髓系细胞成熟缺陷相关的急性口腔炎。
THE EXPERIMENTAL PRODUCTION IN DOGS OF ACUTE STOMATITIS, ASSOCIATED WITH LEUCOPENIA AND A MATURATION DEFECT OF THE MYELOID ELEMENTS OF THE BONE MARROW.
机构信息
Hospital of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1935 Jan 31;61(2):173-82. doi: 10.1084/jem.61.2.173.
Abstract
An ulcerative stomatitis associated with leucopenia and granulopenia can be induced in dogs by means of a diet causing black tongue. The decrease of circulating leucocytes is due to a suppression of maturation of the erythropoietic elements of the bone marrow. The changes as a whole have a resemblance to those occurring in human beings with acute agranulocytosis.
摘要
一种与白细胞减少症和粒细胞减少症相关的溃疡性口炎可通过导致黑舌的饮食在犬中诱发。循环白细胞减少是由于骨髓中红系细胞成熟受到抑制所致。总的来说，这些变化与人类急性粒细胞缺乏症发生的变化相似。
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