磺胺吡啶、烟酸和辅酶与金黄色葡萄球菌生长的关系。
THE RELATIONSHIP OF SULFAPYRIDINE, NICOTINIC ACID, AND COENZYMES TO THE GROWTH OF STAPHYLOCOCCUS AUREUS.
机构信息
Department of Medicine of the Presbyterian Hospital and the College of Physicians and Surgeons, Columbia University, New York.
出版信息
J Exp Med. 1940 Jun 30;72(1):91-7. doi: 10.1084/jem.72.1.91.
Abstract
Our studies indicate that sulfapyridine modifies the normal metabolism of a bacterium. Coenzymes inhibit the effect of sulfapyridine on the growth of staphylococcus in Knight's medium. Nicotinic acid does not interfere with the action of sulfapyridine under the same conditions. The possible relation of sulfapyridine, nicotinic acid, and coenzymes in relation to bacterial growth is discussed.
摘要
我们的研究表明，磺胺吡啶会改变细菌的正常代谢。辅酶会抑制磺胺吡啶在 Knight 培养基中对金黄色葡萄球菌生长的作用。在相同条件下，烟酸不会干扰磺胺吡啶的作用。讨论了磺胺吡啶、烟酸和辅酶与细菌生长的可能关系。
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