氢离子浓度对白细胞吞噬作用和黏附性的影响。
EFFECT OF THE HYDROGEN ION CONCENTRATION ON THE PHAGOCYTOSIS AND ADHESIVENESS OF LEUCOCYTES.
机构信息
Laboratory of Applied Physiology, Harvard Medical School, Boston.
出版信息
J Gen Physiol. 1922 Nov 20;5(2):169-79. doi: 10.1085/jgp.5.2.169.
Abstract
- Immediately after coming into contact with glass, leucocytes are most adhesive at pH 8.0 or > 8.0. 2. Agglutination of leucocytes increases with increasing H ion concentration from pH 8.0 to 6.0. 3. In phagocytosis experiments where leucocytes creep about on the slide picking up articles the optimum pH is 7.0. Here ameboid movement is probably the limiting factor. 4. The optimum for phagocytosis of quartz from suspension is on the acid side of neutrality at or near pH 6.7. 5. Phagocytosis of quartz increases with the acidity, while adhesiveness of leucocytes to glass increases with the alkalinity.
摘要
白细胞与玻璃接触后，在 pH8.0 或更高时最具粘性。
白细胞的凝集作用随着 H 离子浓度从 pH8.0 增加到 6.0 而增加。
在白细胞在载玻片上爬行以吞噬颗粒的吞噬实验中，最佳 pH 值为 7.0。在这里，阿米巴样运动可能是限制因素。
悬浮液中石英的最佳吞噬 pH 值在中性偏酸一侧，接近 pH6.7。
石英的吞噬作用随着酸度的增加而增加，而白细胞对玻璃的粘性则随着碱性的增加而增加。
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