双链多核苷酸作为干扰素诱导物。
Double-stranded polynucleotides as interferon inducers.
机构信息
Division of Virus and Cell Biology Research, Merck Institute for Therapeutic Research, West Point, Pennsylvania 19486.
出版信息
J Gen Physiol. 1970 Jul 1;56(1):90-6. doi: 10.1085/jgp.56.1.90.
Abstract
A discussion of factors considered influential in making a polynucleotide an efficient inducer of interferon was presented. These factors were double-strandedness of the polynucleotides, the sugar moiety of the polynucleotides, thermal stability, resistance to enzymatic degradation, and molecular size of the polynucloetides. Recent developments concerning interferon induction during virus infection were also discussed.
摘要
本文讨论了影响多核苷酸成为有效干扰素诱导物的因素。这些因素包括多核苷酸的双链性、多核苷酸的糖部分、热稳定性、抗酶降解性和多核苷酸的分子大小。还讨论了病毒感染期间干扰素诱导的最新进展。
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Double-stranded polynucleotides as interferon inducers.双链多核苷酸作为干扰素诱导物。
J Gen Physiol. 1970 Jul 1;56(1):90-6. doi: 10.1085/jgp.56.1.90.
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