Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Clin Exp Dermatol. 2010 Jun;35(4):e113-5. doi: 10.1111/j.1365-2230.2009.03725.x. Epub 2009 Oct 23.
Lentigines are characterized by brown macules developing due to increased proliferation of melanocytes in the dermoepidermal junction. Many drugs, including immunosuppressants and immunomodulators, have been shown to cause generalized lentiginosis. We describe a case of lentiginosis induced by cancer chemotherapy, an extremely rare occurrence.
雀斑样痣的特征是棕色斑点,由于表皮与真皮交界处黑素细胞增殖增加而发展。许多药物,包括免疫抑制剂和免疫调节剂,已被证明可引起全身性雀斑样痣。我们描述了一例由癌症化疗引起的雀斑样痣,这是一种极其罕见的情况。