Luff B J, Harris R D, Wilkinson J S, Wilson R, Schiffrin D J
Opt Lett. 1996 Apr 15;21(8):618-20. doi: 10.1364/ol.21.000618.
We present measurements of biomolecular binding reactions, using a new type of integrated-optical biosensor based on a planar directional coupler structure. The device is fabricated by Ag(+) - Na(+) ion exchange in glass, and definition of the sensing region is achieved by use of transparent fluoropolymer isolation layers formed by thermal evaporation. The suitability of the sensor for application to the detection of environmental pollutants is considered.
我们展示了使用一种基于平面定向耦合器结构的新型集成光学生物传感器对生物分子结合反应的测量。该器件通过玻璃中的Ag(+) - Na(+)离子交换制造,传感区域的定义是通过使用热蒸发形成的透明含氟聚合物隔离层来实现的。我们考虑了该传感器应用于检测环境污染物的适用性。