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自发性脑出血后的死亡与功能转归。一项对166例患者进行多因素分析的前瞻性研究。

Death and functional outcome after spontaneous intracerebral hemorrhage. A prospective study of 166 cases using multivariate analysis.

作者信息

Daverat P, Castel J P, Dartigues J F, Orgogozo J M

机构信息

Service de Rééducation Fonctionnelle, Hôpital Pellegrin, Bordeaux, France.

出版信息

Stroke. 1991 Jan;22(1):1-6. doi: 10.1161/01.str.22.1.1.

Abstract

Using death and functional status as end points, we prospectively analyzed the outcome 6 months after spontaneous intracerebral hemorrhage in 166 patients admitted to an acute-care stroke unit on the first day of their stroke. Seventy-one patients (43%) died, 69 (42%) had a satisfactory outcome, and 26 (16%) had a poor functional outcome. Early (30-day) survival was correlated with morphologic parameters on the initial computed tomogram (hemorrhage size, midline shift, and intraventricular spread of the hemorrhage), while later (6-month) survival was correlated with age. Using logistic regression, we found five independent predictors of satisfactory outcome at 6 months: age, hemorrhage size, intraventricular spread of the hemorrhage, limb paresis, and communication disorders. Of these, age was the most important predictor by far.

摘要

以死亡和功能状态作为终点,我们对166例在卒中首日入住急性护理卒中单元的自发性脑出血患者进行了前瞻性分析,观察其6个月后的结局。71例患者(43%)死亡,69例(42%)结局良好,26例(16%)功能结局较差。早期(30天)生存率与初始计算机断层扫描的形态学参数(出血大小、中线移位和出血的脑室内扩散)相关,而后期(6个月)生存率与年龄相关。通过逻辑回归分析,我们发现了6个月时结局良好的5个独立预测因素:年龄、出血大小、出血的脑室内扩散、肢体轻瘫和交流障碍。其中,年龄是迄今为止最重要的预测因素。

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