Harmanli Ozgur H, Tunitsky Elena, Esin Sertac, Citil Ayse, Knee Alexander
Department of Obstetrics and Gynecology, Tufts University School of Medicine, Baystate Medical Center, Springfield, MA, USA.
Am J Obstet Gynecol. 2009 Nov;201(5):536.e1-7. doi: 10.1016/j.ajog.2009.07.048.
The purpose of this study was to compare perioperative outcome measures of laparoscopic supracervical (LSH) and total hysterectomies (TLH).
This is a retrospective analysis of 1016 LSHs and TLHs at a tertiary medical center between November 1999 and August 2008 in a multivariate logistic regression model.
Overall, the groups were similar. Most of the perioperative outcome measures did not differ statistically between the groups. However, the risk of serious complications was higher for TLH (5.8% vs 2.5%; odds ratio [OR], 2.72; 95% confidence interval [CI], 1.35-5.49). Specifically, urinary tract injury occurred more frequently in TLH (2.2% vs 0.5%; OR, 4.75; 95% CI, 1.21-18.56). Conversion to laparotomy was significantly more common in TLH (5.8% vs 4.1%; OR, 2.25; 95% CI, 1.20-4.22).
In this largest comparison, short-term morbidity of TLH and LSH is overall similar. TLH presents a clinically small, but statistically significant, increased risk of urinary tract injury and conversion to laparotomy.
本研究旨在比较腹腔镜次全子宫切除术(LSH)和全子宫切除术(TLH)的围手术期结局指标。
这是一项对1999年11月至2008年8月在一家三级医疗中心进行的1016例LSH和TLH手术的回顾性分析,采用多因素逻辑回归模型。
总体而言,两组相似。大多数围手术期结局指标在两组间无统计学差异。然而,TLH发生严重并发症的风险更高(5.8%对2.5%;优势比[OR],2.72;95%置信区间[CI],1.35 - 5.49)。具体而言,TLH中尿路损伤更频繁发生(2.2%对0.5%;OR,4.75;95%CI,1.21 - 18.56)。TLH中转开腹手术明显更常见(5.8%对4.1%;OR,2.25;95%CI,1.20 - 4.22)。
在这项最大规模的比较中,TLH和LSH的短期发病率总体相似。TLH存在临床上虽小但在统计学上有显著意义的尿路损伤和转开腹手术风险增加。