Chassin Ludovic Jean, Wilinska Malgorzata E, Hovorka Roman
Department of Paediatrics, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
J Diabetes Sci Technol. 2007 Jul;1(4):570-3. doi: 10.1177/193229680700100415.
Development of the external artificial pancreas (AP) is anticipated to be incremental, starting with simple and progressing to more complex applications incorporating exercise periods of various duration and intensity. Most studies investigating the effect of exercise on glucose excursions in subjects with type 1 diabetes either explored moderate exercise, which exerts different effects compared to intense exercise, or did not adopt continuous glucose monitoring combined with frequent plasma glucose measurements. Such studies could provide vital information. Performance of continuous glucose monitors during intense exercise could be evaluated to a greater extent. Frequently sampled blood glucose would facilitate better understanding of the relationship between intense exercise and metabolic processes, providing helpful information to patients with type 1 diabetes, clinicians, and researchers involved in the development of the AP.
预计外部人工胰腺(AP)的发展将是渐进式的,从简单应用开始,逐步发展到包含不同持续时间和强度运动阶段的更复杂应用。大多数研究1型糖尿病患者运动对血糖波动影响的研究,要么探讨的是中度运动(与高强度运动产生的效果不同),要么没有采用连续血糖监测并结合频繁的血浆葡萄糖测量。这类研究可以提供重要信息。高强度运动期间连续血糖监测仪的性能可以得到更大程度的评估。频繁采集的血糖数据将有助于更好地理解高强度运动与代谢过程之间的关系,为1型糖尿病患者、临床医生以及参与AP开发的研究人员提供有用信息。