Stone Treatment Centre, Craigavon Area Hospital, Portadown, Northern Ireland, UK.
BJU Int. 2010 Mar;105(5):692-6. doi: 10.1111/j.1464-410X.2009.08919.x. Epub 2009 Nov 3.
To determine the benefits of a slower shockwave (SW) delivery rate of 70 shocks/min on the treatment efficiency and cost-effectiveness of extracorporeal SW lithotripsy (ESWL).
Patients who had ESWL for their upper urinary tract radio-opaque calculi were categorized into two groups: slow (70 SW/min) and fast (100 SW/min) delivery rate. All treatment was carried out using a lithotripter (Model S, Dornier MedTech, Wessling, Germany) as an outpatient procedure with no anaesthesia or sedation. The groups were followed for > or =6 months. The primary outcomes compared were the stone-free rate, re-treatment rate, additional procedure rate, perceived cost and actual cost. Clinical success was defined as stone-free status or asymptomatic insignificant residual fragments of <3 mm. Perceived cost was defined as the cost of ESWL alone, and actual cost included the cost of additional procedures and overhead costs to result in clinical success.
In all, the study included 102 patients, categorized into the fast (51) and slow (51) rate groups. The groups were comparable in terms of sex, age, body mass index, stone size and stone location. The slow group had a significantly better stone-free rate (67% vs 25.5%, P = 0.002, chi-square), fewer mean shocks to clinical success (3045 vs 4414, P < 0.001, U-test), lower re-treatment rate (22% vs 45%P = 0.013, chi -square), a lower additional procedure rate (12% vs 29%, P = 0.02, chi-square), greater efficiency quotient (0.51 vs 0.16) than the fast group. The mean perceived cost of ESWL (GB pound 297 vs 394 pounds, P = 0.013, U-test) and the mean actual cost of the slow group were significantly less (496 pounds vs 1002 pounds, P = 0.001, U-test).
Slowing the SW delivery rate to 70/min significantly reduced the actual cost by half and improved treatment efficiency.
确定较慢的冲击波(SW)传递率(70 次/分钟)对上尿路不透射线结石的体外冲击波碎石术(ESWL)治疗效率和成本效益的影响。
将接受 ESWL 治疗上尿路放射性结石的患者分为两组:慢(70 SW/分钟)和快(100 SW/分钟)传递率。所有治疗均在无麻醉或镇静的情况下在碎石机(Model S,Dornier MedTech,Wessling,德国)上作为门诊程序进行。两组均随访>或=6 个月。比较的主要结果是无结石率、再治疗率、附加程序率、感知成本和实际成本。临床成功定义为无结石状态或无症状的<3mm 残余结石碎片。感知成本定义为 ESWL 本身的成本,实际成本包括附加程序和导致临床成功的间接费用。
共有 102 例患者入组,分为快(51 例)和慢(51 例)组。两组在性别、年龄、体重指数、结石大小和结石位置方面具有可比性。慢组的无结石率显著更好(67%比 25.5%,P=0.002,卡方检验),达到临床成功所需的平均冲击波次数更少(3045 次比 4414 次,P<0.001,U 检验),再治疗率更低(22%比 45%,P=0.013,卡方检验),附加程序率更低(12%比 29%,P=0.02,卡方检验),效率商更高(0.51 比 0.16)。慢组的 ESWL 感知成本均值(GB 磅 297 比 394 磅,P=0.013,U 检验)和慢组的实际成本均值均显著较低(496 磅比 1002 磅,P=0.001,U 检验)。
将 SW 传递率降低至 70 次/分钟可使实际成本降低一半,并提高治疗效率。