Salvatierra O, McVicar J, Melzer J, Amend W, Vincenti F, Tomlanovich S, Husing R, Rabkin J, Garovoy M
Transplant Service, University of California, San Francisco 94143-0116.
Transplant Proc. 1991 Feb;23(1 Pt 2):1024-6.
A combined DST-sequential CyA therapy protocol has been described that results in optimum graft survival for 1- and 2-haplotype mismatched living related donor-recipient combinations. In addition to the excellent graft survival obtained through 4 years, lower prednisone and CyA dosage levels are achieved with significantly decreased infection rates during the posttransplant period.
已经描述了一种联合的二氢速甾醇-序贯环孢素A治疗方案,该方案可使1个单倍型和2个单倍型错配的活体亲属供受者组合获得最佳的移植物存活。除了4年期间获得的出色移植物存活外,还实现了较低的泼尼松和环孢素A剂量水平,且移植后期间的感染率显著降低。