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[一名未成年活体肝供体的案例:精神问题与评估]

[The case of a living liver donor who was underage: psychiatric issues and evaluation].

作者信息

Honda Nami, Awata Shuichi, Matsuoka Hiroo

机构信息

Department of Psychiatry, Tohoku University Graduate School of Medicine.

出版信息

Seishin Shinkeigaku Zasshi. 2009;111(8):930-7.

Abstract

We report a case in which a healthy 18-year-old girl acted as a liver donor for her mother, who had a terminal hepatic illness with a one-year survival probability of 2% without liver transplantation. The daughter, who was the only relative to have a blood type compatible with her mother, offered to donate after the surgeons explained the situation. Our ethical committee required a psychiatrist to evaluate her psychiatric status and competence, and address ethical concerns. We assessed elements of informed consent: disclosure of information, competence, and voluntariness, as well as psychiatric problems and the psychosocial status. The disclosure of information was adequate. The girl's competence was of a sufficient level for her to appreciate that the procedure could have negative results on both her and her mother. She was able to logically assess the consequences of having the operation and those of declining it. It was very difficult to evaluate whether she was undergoing the procedure completely voluntarily, because she was the only one with a blood type compatible with her mother, who was near death, and because the girl was underage. Psychological issues related to her age were that she depended on her family economically and psychologically, and that the opinions of her family influenced her. In this case, we concluded that she had consented voluntarily, because there was no coercion and no unjust pressure to donate, and because she understood that consent could be withdrawn at any time. Although she was underage and the psychological assessment revealed that she experienced some conflict in this difficult situation, her competence was considered intact. Medical evaluation and laboratory testing were satisfactory, and the ethical committee determined that she was suitable to donate. The operation was performed and was successful. The Japanese Transplantation Society has since established ethical guidelines regarding potential living donors who are underage; one precondition for donation is that a psychiatrist must evaluate whether or not the competence of the donor is equal to that of an adult. As the literature contains no reports of the evaluation of potential donors who are underage, we need to consider the format and contents of such psychiatric evaluations and ethical concerns.

摘要

我们报告了一例病例,一名健康的18岁女孩为她患有终末期肝病的母亲充当肝脏供体。其母亲若不进行肝移植,一年内存活概率为2%。女儿是唯一血型与母亲匹配的亲属,在外科医生解释情况后主动提出捐赠。我们的伦理委员会要求精神科医生评估她的精神状态和行为能力,并解决伦理问题。我们评估了知情同意的要素:信息披露、行为能力和自愿性,以及精神问题和社会心理状况。信息披露是充分的。女孩的行为能力足以使她理解该手术可能对她自己和她母亲产生负面结果。她能够从逻辑上评估进行手术和拒绝手术的后果。很难评估她是否完全自愿接受该手术,因为她是唯一血型与濒死母亲匹配的人,且女孩尚未成年。与她年龄相关的心理问题是,她在经济和心理上依赖家庭,且家庭意见对她有影响。在这种情况下,我们得出结论,她是自愿同意的,因为不存在强迫捐赠或不正当压力,且她明白同意可以随时撤回。尽管她尚未成年,且心理评估显示她在这种困境中经历了一些冲突,但她的行为能力被认为是完整的。医学评估和实验室检查结果令人满意,伦理委员会认定她适合捐赠。手术得以进行且很成功。此后,日本移植学会制定了关于未成年潜在活体供体的伦理准则;捐赠的一个前提条件是精神科医生必须评估供体的行为能力是否等同于成年人。由于文献中没有关于未成年潜在供体评估的报告,我们需要考虑此类精神科评估的形式和内容以及伦理问题。

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