大肠杆菌中murR阻遏物的两种自动调节模式。
Two modes of autoregulation of the murR repressor in Escherichia coli.
作者信息
Ishii Daiki, Ishihama Akira, Yamamoto Kaneyoshi
机构信息
Department of Frontier Bioscience, Hosei University, Tokyo, Japan.
出版信息
Biosci Biotechnol Biochem. 2009 Nov;73(11):2528-30. doi: 10.1271/bbb.90421. Epub 2009 Nov 7.
The murPQ operon of Escherichia coli encoding the enzymes for degradation of MurNAc is derepressed by MurR (YfeT) in the presence of MurNAc-6-phosphate. MurR also represses its own expression. We found that murR is stimulated in rich medium. This activation involves MurR and most of the IIBC components of the phosphotransferase system, suggesting auto-induction of murR by an activated form of MurR.
大肠杆菌中编码用于降解MurNAc的酶的murPQ操纵子在6-磷酸MurNAc存在的情况下被MurR（YfeT）去阻遏。MurR还抑制其自身的表达。我们发现murR在丰富培养基中受到刺激。这种激活涉及MurR和磷酸转移酶系统的大多数IIBC组分，提示murR被激活形式的MurR自身诱导。
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