Jones J, Hampel C
Urologische Klinik und Poliklinik, Universitätsmedizin, Johannes-Gutenberg-Universität, Langenbeckstrasse 1, 55131, Mainz, Deutschland.
Urologe A. 2009 Dec;48(12):1459-63. doi: 10.1007/s00120-009-2159-1.
The number of patients on the renal transplant waiting list has remained constantly high. In this article we highlight two strategies to extend the donor pool and focus on AB0 incompatible and cross-over renal transplantation. Increased immunologic knowledge and improved therapeutic management have facilitated successful AB0 incompatible renal transplantation with very good long-term results. However, this method has only been applied in very few German transplant centers and should be explored further. The term cross-over transplantation implies the exchange of organs between two otherwise incompatible couples enabling compatible transplantation in both couples. The German transplantation law allows only living transplantation in emotionally related couples. However, in specific cases of close interpersonal relationships cross-over transplantation between two couples is acceptable.
肾移植等待名单上的患者数量一直居高不下。在本文中，我们重点介绍两种扩大供体库的策略，并着重探讨AB0血型不相容和交叉肾移植。免疫学知识的增加和治疗管理的改善促进了AB0血型不相容肾移植的成功，长期效果良好。然而，这种方法仅在德国极少数移植中心应用，应进一步探索。交叉移植这一术语意味着在两对原本不相容的夫妇之间交换器官，使两对夫妇都能进行相容性移植。德国移植法仅允许在有情感关系的夫妇之间进行活体移植。然而，在特定的亲密人际关系案例中，两对夫妇之间的交叉移植是可以接受的。
