Spies Christian, Wong Melvin
The Queen's Medical Center, Queen's Heart Physician Practice, 550 S Beretania Street, Suite 300, Honolulu, HI 96813, USA.
Expert Rev Cardiovasc Ther. 2009 Nov;7(11):1455-67. doi: 10.1586/erc.09.114.
Patent foramen ovale has been suggested to be a risk factor for cryptogenic stroke by means of paradoxical embolism. The data, however, are complex, conflicting and largely unavailable. In this review, we attempt to summarize the existing data separately for the questions of whether patent foramen ovale is associated with cryptogenic stroke and whether it is a risk factor for a first ischemic stroke and for recurrent strokes. Treatment options will be discussed, and the different viewpoints from the two specialists mainly involved in the care of those complex patients (neurologists and cardiologists) will be provided.
卵圆孔未闭已被认为是通过反常栓塞导致隐源性卒中的一个危险因素。然而，相关数据复杂、相互矛盾且大多难以获取。在本综述中，我们试图分别总结关于卵圆孔未闭是否与隐源性卒中相关以及它是否是首次缺血性卒中和复发性卒中的危险因素这两个问题的现有数据。我们将讨论治疗选择，并提供主要参与这些复杂患者治疗的两位专家（神经科医生和心脏科医生）的不同观点。
