Poniatowski B C
J Intraven Nurs. 1991 Jan-Feb;14(1):30-5.
Chronic moderate-to-severe pain is a common problem that directly impacts on the quality of life of the patient with a malignant neoplasm. It is estimated that pain is a major symptom in 70% of cancer patients. Continuous subcutaneous infusion of opioids has proved to be an efficacious and safe method to control the chronic pain of the home-bound and hospitalized patient. A wide variety of opioids can be used, including morphine, hydromorphone, and methadone. The subcutaneous route offers economic as well as physiologic advantages. The primary disadvantage to the system is volume limitations. Competent nursing management of the subcutaneous infusion helps to maximize the effectiveness of the opioid, thereby improving the patient's quality of life.
慢性中重度疼痛是一个常见问题，直接影响恶性肿瘤患者的生活质量。据估计，疼痛是70%癌症患者的主要症状。持续皮下输注阿片类药物已被证明是控制居家和住院患者慢性疼痛的一种有效且安全的方法。可使用多种阿片类药物，包括吗啡、氢吗啡酮和美沙酮。皮下途径具有经济和生理优势。该系统的主要缺点是容量限制。对皮下输注进行有效的护理管理有助于最大限度地提高阿片类药物的疗效，从而改善患者的生活质量。
