Department of Pediatrics and Pediatric Surgery, Pediatric Endocrinology Section, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
J Pediatr (Rio J). 2009 Nov-Dec;85(6):490-4. doi: 10.2223/JPED.1942. Epub 2009 Nov 9.
To evaluate clinical and laboratory profiles of patients with type 1 diabetes mellitus in three public hospitals in São Paulo, Brazil, since type 1 diabetes mellitus is a chronic illness that occurs mainly in the pediatric age group in the Brazilian population.
Cross-sectional study with patients followed up in reference centers in São José do Rio Preto (FAMERP), Campinas (UNICAMP) and São Paulo (Conjunto Hospitalar do Mandaqui). Data about gender, age, diabetes duration, daily insulin dose, number of daily insulin injections, and glycosylated hemoglobin (HbA1c) were analyzed.
Two hundred and thirty-nine patients (131 females) were evaluated; mean age was 13.1+/-4.7 years and mean diabetes duration was 6.6+/-4.2 years. Daily insulin doses ranged from 0.1 to 1.78 units/kg/day (0.88+/-0.28), and 180 (74.7%) patients had two daily injections. HbA1c ranged from 4.6 to 17.9% (10.0+/-2.3%).
Although the hospitals included in this study are excellence centers for the follow-up of patients with diabetes in three municipalities in the state of São Paulo, one of the most developed states in Brazil, blood glucose control evaluated according to HbA1c was not adequate. Findings confirm that, despite the efforts of all the professionals involved, great challenges still lie ahead.
评估巴西圣保罗 3 家公立医院 1 型糖尿病患者的临床和实验室特征，因为 1 型糖尿病是一种慢性病，主要发生在巴西人口的儿科年龄组。
这是一项横断面研究，对圣若泽-里波特（FAMERP）、坎皮纳斯（UNICAMP）和圣保罗（曼达基医院联合体）的参考中心的患者进行随访。分析了性别、年龄、糖尿病病程、每日胰岛素剂量、每日胰岛素注射次数和糖化血红蛋白（HbA1c）等数据。
共评估了 239 名患者（131 名女性）；平均年龄为 13.1+/-4.7 岁，平均糖尿病病程为 6.6+/-4.2 年。每日胰岛素剂量范围为 0.1 至 1.78 单位/千克/天（0.88+/-0.28），180 名（74.7%）患者每天注射两次。HbA1c 范围为 4.6 至 17.9%（10.0+/-2.3%）。
尽管参与这项研究的医院是巴西圣保罗州三个城市糖尿病患者随访的卓越中心，但作为巴西最发达的州之一，根据 HbA1c 评估的血糖控制并不理想。研究结果证实，尽管所有相关专业人员都付出了努力，但仍面临着巨大的挑战。
