Department of Radiology, Weill Cornell Medical College/New York Presbyterian Hospital, New York, NY 10065, USA.
Pediatr Radiol. 2010 Mar;40(3):366-70. doi: 10.1007/s00247-009-1456-6. Epub 2009 Nov 10.
Pulmonary blastoma is a rare malignant primary lung neoplasm typically seen in adults that accounts for 0.3-1.3% of lung malignancies. It has been categorized as a subtype of sarcomatoid carcinoma according to the current World Health Organization Classification of Lung Tumours and is distinct from the more common pediatric lung tumor pleuropulmonary blastoma. We report a case of neonatal pulmonary blastoma, illustrating the imaging characteristics of this rare tumor. The subject of pediatric lung masses is confusing because the terms pleuropulmonary blastoma and pulmonary blastoma have been used interchangeably in previously reported cases. We recommend use of the current WHO classification to differentiate these lesions as additional cases are described. Additionally, we discuss distinctive cytogenetic features of this case.
肺胚细胞瘤是一种罕见的恶性原发性肺肿瘤，通常见于成年人，占肺部恶性肿瘤的 0.3-1.3%。根据目前的《世界卫生组织肺部肿瘤分类》，它被归类为肉瘤样癌的一个亚型，与更常见的小儿肺部肿瘤胸膜肺胚细胞瘤不同。我们报告了一例新生儿肺胚细胞瘤，说明了这种罕见肿瘤的影像学特征。由于在以前报道的病例中，胸膜肺胚细胞瘤和肺胚细胞瘤这两个术语可以互换使用，因此小儿肺部肿块的问题比较混乱。我们建议使用目前的世卫组织分类来区分这些病变，因为还有更多的病例被描述。此外，我们还讨论了该病例的独特细胞遗传学特征。
