Morimoto T, Imhof H G, Wiestler O D
Laboratory of Microsurgery, University of Zurich, Switzerland.
Microsurgery. 1991;12(1):46-54. doi: 10.1002/micr.1920120110.
Reconstruction of the carotid bifurcation was performed in rats using y-shaped microvascular grafts in an attempt to examine the feasibility of using such grafts in intracranial vascular reconstruction, especially for vessels with bifurcations. Twenty y-shaped microarterial grafts were obtained from the carotid bifurcation of donor rats, while 20 y-shaped microvenous grafts were obtained from the femoral veins of the rats. The patency rate of arterial grafts and venous grafts were 75% and 97%, respectively. Anastomotic aneurysms frequently occurred in both arterial grafts (45%) and venous grafts (60%). Results of histological examinations concluded that these aneurysms were false aneurysms. We discuss the reasons for aneurysm formation and technical issues that might improve the experimental results with regard to patency and aneurysm formation.
在大鼠身上使用Y形微血管移植物进行颈动脉分叉重建，以检验此类移植物用于颅内血管重建（特别是用于有分叉的血管）的可行性。从供体大鼠的颈动脉分叉处获取20个Y形微动脉移植物，同时从大鼠的股静脉获取20个Y形微静脉移植物。动脉移植物和静脉移植物的通畅率分别为75%和97%。动脉移植物（45%）和静脉移植物（60%）中均频繁出现吻合口动脉瘤。组织学检查结果表明这些动脉瘤为假性动脉瘤。我们讨论了动脉瘤形成的原因以及可能改善通畅率和动脉瘤形成方面实验结果的技术问题。
