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成人坐骨神经注射损伤:安乃近是神经的敌人吗?

Sciatic injection injuries in adults: is dipyrone a foe to nerve?

作者信息

Sevim Serhan, Kaleagasi Hakan

机构信息

Mersin University, Faculty of Medicine, Department of Neurology, Mersin, Turkey.

出版信息

Acta Neurol Belg. 2009 Sep;109(3):210-3.

PMID:19902815
Abstract

Sciatic nerve injury is an iatrogenic and rare complication of intragluteal injections. There are a few reports on the subject in adults. Data were collected for eight years from patients referred to our electroneuromyography laboratory. Twenty-eight adult patients (20 males and 8 females) diagnosed with post-injection injuries were identified by history, clinical and electrophysiological findings. A complete history was available in 26, all reporting sudden pain and subsequent radiation of pain and numbness in the distribution of the sciatic nerve. In 17 of the 28 the common peroneal portion was affected more severely than the posterior tibial portion; in seven the opposite. Twenty-three patients were able to name the injected drug, and dipyrone (metamizole) specifically, as the responsible agent in 11 of them (47,8%). Injection neuropathy is not specific to children only alone and according to our data special attention is needed during intragluteal injections for thin men and/or usage of dipyrone.

摘要

坐骨神经损伤是臀内注射引起的一种医源性罕见并发症。关于该主题在成人中的报道较少。我们从转诊至我们肌电图实验室的患者中收集了八年的数据。通过病史、临床和电生理检查结果,确定了28例诊断为注射后损伤的成年患者(20例男性和8例女性)。26例患者有完整的病史,均报告有突然疼痛,随后坐骨神经分布区域出现疼痛和麻木。28例中有17例腓总神经部分比胫后神经部分受影响更严重;7例情况相反。23例患者能够说出注射的药物,其中11例(47.8%)明确指出是双氯芬酸(安乃近)。注射性神经病变并非仅见于儿童,根据我们的数据,在对瘦男性进行臀内注射和/或使用双氯芬酸时需要特别注意。

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Sciatic injection injuries in adults: is dipyrone a foe to nerve?成人坐骨神经注射损伤:安乃近是神经的敌人吗?
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Iran J Basic Med Sci. 2016 Aug;19(8):829-836.