Maternité Pinard, Hopital Saint Vincent de Paul, Université René Descartes Paris France.
Gynecol Endocrinol. 2009 Nov;25(11):751-6. doi: 10.3109/09513590903230341.
The transitory effect of hormonal treatment is the alleged main reason to criticize progestins (PGS) and combined pills (OP) in the managment of endometriosis. To the contrary their poor efficacy in the long run is often underlined. As a result, medical treatment is too seldom advised in endometriosis. In this article, we shall focus on the analysis of the reasons of the paucity of the medical interest given to progestins, reasons, which are not of a scientific or objective nature. The ultimate aim of this analysis is to develop arguments in favour of continuous administration of hormones as to obtain not simply an anovulation but a state of prolonged amenorrhea much more efficacious than the simple suppression of ovulation too often advised. And, with an emphasis on the fundamental role of surgery in the treatment of endometriosis, to give the greatest consideration to the specific nature of this disease, which is a chronic disease, justifying the long duration of hormonal administration.
激素治疗的短暂效果是批评孕激素 (PGS) 和复方避孕药 (OP) 在子宫内膜异位症治疗中的主要原因。相反，它们的长期疗效不佳经常被强调。因此，子宫内膜异位症的医疗治疗很少被建议。在本文中，我们将重点分析孕激素缺乏医学关注的原因，这些原因不是基于科学或客观性质的。这种分析的最终目的是提出支持激素持续给药的论点，以获得不仅仅是排卵抑制，而是一种比经常建议的简单排卵抑制更有效的长期闭经状态。并且，强调手术在子宫内膜异位症治疗中的核心作用，充分考虑到这种疾病的特殊性，即慢性病，这证明了激素给药的持续时间需要足够长。
