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终末期肾病中的心房颤动:一个新出现的问题。

Atrial fibrillation in end-stage renal disease: an emerging problem.

机构信息

Department of Cardiology, University of Ioannina School of Medicine, Ioannina, Greece.

出版信息

Kidney Int. 2009 Aug;76(3):247-9. doi: 10.1038/ki.2009.144.

DOI:10.1038/ki.2009.144
PMID:19904256
Abstract

End-stage renal disease is associated with considerable cardiovascular morbidity and mortality. Atrial fibrillation (AF) is prevalent among dialysis patients and adversely affects the clinical outcome. Vazquez et al. report an increased prevalence and incidence of AF in patients who commence dialysis, and an independent association between arrhythmia and mortality risk. Moreover, they examined clinical and laboratory parameters associated with AF. This population study may fuel research aiming at the development of novel preventive and treatment strategies.

摘要

终末期肾病与相当大的心血管发病率和死亡率有关。心房颤动(AF)在透析患者中很常见,并对临床结果产生不利影响。Vazquez 等人报告称,开始透析的患者中 AF 的患病率和发病率增加,心律失常与死亡风险之间存在独立关联。此外,他们还检查了与 AF 相关的临床和实验室参数。这项人群研究可能会推动旨在开发新的预防和治疗策略的研究。

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引用本文的文献

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J Am Heart Assoc. 2021 Jun 15;10(12):e019596. doi: 10.1161/JAHA.120.019596. Epub 2021 Jun 2.
2
Anticoagulation in Patients with End-Stage Renal Disease and Atrial Fibrillation: Confusion, Concerns and Consequences.终末期肾病合并心房颤动患者的抗凝治疗:困惑、担忧与后果
J Stroke. 2020 Sep;22(3):306-316. doi: 10.5853/jos.2020.01886. Epub 2020 Sep 29.
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Atrial Fibrillation Characteristics in Patients on Haemodialysis vs. Peritoneal Dialysis.
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Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes.成纤维细胞生长因子23失调晚期钠电流和钙稳态,增强肺静脉心肌细胞的心律失常发生。
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Primary prevention of atrial fibrillation with beta-blockers in patients with end-stage renal disease undergoing dialysis.在接受透析的终末期肾病患者中使用β受体阻滞剂进行心房颤动的一级预防。
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