Department of Medicine, The Artificial Pancreas Center, Philadelphia, Pennsylvania, USA.
Diabetes Technol Ther. 2009 Nov;11(11):745-7. doi: 10.1089/dia.2009.0071.
This study shows the potential of continuous glucose monitoring (CGM) for the detection of hypoglycemia in hospitalized patients.
A Medtronic Diabetes (Northridge, CA) CGMS iPro continuous glucose recorder was inserted into the subcutaneous tissue of a hospitalized orthopedic surgery patient with type 1 diabetes the day after a moderate hypoglycemia event. The interstitial fluid glucose concentration was recorded every 5 min. Both the patient and the hospital staff were blinded to the CGM data. Bedside capillary blood glucose measurements were performed per hospital protocol.
The CGM recorded a repeat severe episode of hypoglycemia the next day. The hospital-defined threshold for hypoglycemia (70 mg/dL) was crossed 4.5 h prior to the patient being found unconscious by the nursing staff.
Data from the CGMS iPro Recorder illustrate the potential benefit of using a real-time CGM in the hospital to detect hypoglycemia in a more timely fashion compared to infrequent point-of-care glucose meter measurements.
本研究显示了连续血糖监测(CGM)在检测住院患者低血糖方面的潜力。
在 1 型糖尿病中度低血糖事件发生后一天,将美敦力糖尿病(加利福尼亚州北岭)CGMS iPro 连续血糖记录器插入到住院骨科手术患者的皮下组织中。间质液葡萄糖浓度每 5 分钟记录一次。患者和医院工作人员均对 CGM 数据不知情。根据医院方案进行床边毛细血管血糖测量。
CGM 记录到次日再次出现严重低血糖事件。医院定义的低血糖阈值(70mg/dL)在护理人员发现患者无意识前 4.5 小时就已经超过。
CGMS iPro 记录器的数据表明,与偶尔的即时血糖仪测量相比,使用实时 CGM 在医院更及时地检测低血糖具有潜在益处。