University Cardiology Department, Medical School, Democritus University of Thrace, Voulgaroktonou 23, 68100 Alexandroupolis, Greece.
Int J Cardiol. 2010 Jun 25;142(1):2-7. doi: 10.1016/j.ijcard.2009.10.031. Epub 2009 Nov 10.
This review attempts to present a focused summary of selected areas of the rapidly growing knowledge regarding the red blood cells role in atherosclerotic plaque progression and instability. A summary of the characteristics of the erythrocyte membranes is provided, followed by a brief review of the in vitro and in vivo work that has helped clarify their role in atherosclerosis. Mechanisms by which erythrocytes enter the atherosclerotic plaque and contribute to its progression and instability are presented. Finally, some elements that may be clinically important regarding erythrocytes in coronary artery disease are discussed.
这篇综述试图重点总结红细胞在动脉粥样硬化斑块进展和不稳定中的作用方面快速增长的知识领域。本文首先概述了红细胞膜的特征，然后简要回顾了有助于阐明其在动脉粥样硬化中作用的体外和体内研究。本文介绍了红细胞进入动脉粥样硬化斑块并促进其进展和不稳定的机制。最后，讨论了与冠心病中红细胞相关的一些可能具有临床重要性的因素。
