Medical University Berlin, Charité Campus Buch, Franz-Volhard-Klinik for Cardiology, HELIOS Klinikum Berlin-Buch, Germany.
Medical University Berlin, Charité Campus Buch, Franz-Volhard-Klinik for Cardiology, HELIOS Klinikum Berlin-Buch, Germany.
Int J Cardiol. 2010 Nov 19;145(2):308-309. doi: 10.1016/j.ijcard.2009.10.044. Epub 2009 Nov 10.
Takotsubo cardiomyopathy (TTC), which is characterized by transient left ventricular impairment in absence of coronary artery disease, is usually associated with emotional or physical stress, supposing that catecholamines are involved in pathophysiology. The present article reports on two cases with characteristic features of TTC following nasal application of epinephrine during nasal surgery. Both subjects serially underwent cardiovascular magnetic resonance, which revealed myocardial vasodilatation, capillary leak and regional edema in the acute state and ruled out focal necrosis. Thus, the present cases both stress the catecholamine hypothesis in the pathogenesis of TTC and underline the potential of CMR to diagnose and monitor TTC.
心尖球形综合征（TTC）的特征为左心室短暂性障碍，而无冠状动脉疾病，通常与情绪或身体压力有关，推测儿茶酚胺参与了其病理生理学过程。本文报道了 2 例在鼻外科手术中鼻内应用肾上腺素后出现 TTC 特征的病例。这 2 例患者均连续接受了心血管磁共振检查，结果显示在急性期存在心肌血管扩张、毛细血管渗漏和区域性水肿，排除了局灶性坏死。因此，本病例均强调了儿茶酚胺在 TTC 发病机制中的假说，并强调了 CMR 诊断和监测 TTC 的潜力。
