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Successful transfer of donor-specific transplantation tolerance by adoptive transfer of fully allogeneic chimeric bone marrow.

作者信息

Wren S M, Hronakes M L, Ildstad S T

机构信息

Department of Surgery, University of Pittsburgh, School of Medicine, Pennsylvania 15261.

出版信息

Transplant Proc. 1991 Feb;23(1 Pt 1):735-6.

PMID:1990670
Abstract
摘要

相似文献

1
Successful transfer of donor-specific transplantation tolerance by adoptive transfer of fully allogeneic chimeric bone marrow.通过完全异基因嵌合骨髓的过继转移成功实现供体特异性移植耐受的转移。
Transplant Proc. 1991 Feb;23(1 Pt 1):735-6.
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Extended skin allo- and xenograft survival in mice treated with rapamycin, antilymphocyte serum, and donor-specific bone marrow transfusion.用雷帕霉素、抗淋巴细胞血清和供体特异性骨髓输注治疗的小鼠中皮肤同种异体和异种移植物存活期延长
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Fate of long-surviving allografts in tolerant recipients induced by fractionated lymphoid irradiation, donor bone marrow cell infusion, and FK 506 after retransplantation in dogs.经分次淋巴照射、供体骨髓细胞输注及FK 506诱导产生耐受的受体犬再次移植后长期存活同种异体移植物的转归
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Durable mixed allogeneic chimerism and tolerance by a nonlethal radiation-based cytoreductive approach.通过基于非致死性辐射的细胞减灭方法实现持久的混合异体嵌合和耐受。
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Induction of stable long-term mixed hematopoietic chimerism following nonmyeloablative conditioning with T cell-depleting antibodies, cyclophosphamide, and thymic irradiation leads to donor-specific in vitro and in vivo tolerance.使用去除T细胞的抗体、环磷酰胺和胸腺照射进行非清髓性预处理后诱导稳定的长期混合造血嵌合状态,可导致供体特异性的体外和体内耐受。
Biol Blood Marrow Transplant. 2001;7(12):646-55. doi: 10.1053/bbmt.2001.v7.pm11787527.
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Tolerance induction through simultaneous double bone marrow transplantation with two-signal blockade.通过双信号阻断联合双骨髓移植诱导耐受。
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Improved large burn therapy with reduced mortality following an associated septic challenge by early excision and skin allografting using donor-specific tolerance.通过早期切除和使用供体特异性耐受性的皮肤同种异体移植改善大面积烧伤治疗,降低败血症相关挑战后的死亡率。
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