体重指数与 100 万美国成年人的自杀风险。
Body mass index and risk of suicide among one million US adults.
机构信息
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA 02446, USA.
出版信息
Epidemiology. 2010 Jan;21(1):82-6. doi: 10.1097/EDE.0b013e3181c1fa2d.
BACKGROUND
Body mass index (BMI) has been linked with both increased and decreased risk of suicide attempts and deaths.
METHODS
In a prospective cohort study of 1.1 million adults, participants reported their anthropometric and other characteristics in 1982. Participants were followed for cause-specific mortality through 2004.
RESULTS
A total of 2231 participants died of suicide during 21.6 million person-years of follow-up. Compared with a BMI of 18.5-22.9 kg/m(2), adjusted hazard ratios for completed suicide were 0.99 (95% confidence interval = 0.72-1.37), 0.78 (0.69-0.88), 0.73 (0.65-0.82), 0.72 (0.62-0.83), 0.77 (0.65-0.92), and 0.55 (0.36-0.83) for BMI values <18.5, 23.0-24.9, 25.0-27.4, 27.5-29.9, 30.0-34.9, and >or=35.0 kg/m(2), respectively. The relationship was consistent among men and women and across geographic regions, but was limited to married individuals (test for interaction, P = 0.009).
CONCLUSIONS
The risk of death from suicide is inversely related to BMI in middle-aged and older adults.
背景
体重指数（BMI）与自杀未遂和自杀死亡的风险增加和降低均有关联。
方法
在一项对 110 万成年人的前瞻性队列研究中，参与者在 1982 年报告了他们的人体测量学和其他特征。参与者在 2004 年之前被跟踪随访特定原因的死亡率。
结果
在 2160 万人年的随访期间，共有 2231 名参与者死于自杀。与 BMI 为 18.5-22.9 kg/m(2)相比，调整后的自杀完成的风险比为 0.99（95%置信区间=0.72-1.37）、0.78（0.69-0.88）、0.73（0.65-0.82）、0.72（0.62-0.83）、0.77（0.65-0.92）和 0.55（0.36-0.83），分别对应 BMI 值<18.5、23.0-24.9、25.0-27.4、27.5-29.9、30.0-34.9 和≥35.0 kg/m(2)。这种关系在男性和女性以及在不同地理区域中均一致，但仅限于已婚个体（交互检验，P=0.009）。
结论
在中年和老年人中，自杀死亡的风险与 BMI 呈负相关。
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