2-吡啶甲醛与γ-羟基-α,β-炔酸酯之间的环状缩醛形成反应
Cyclic Acetal Formation Between 2-Pyridinecarboxaldehyde and gamma-Hydroxy-alpha,beta-Acetylenic Esters.
作者信息
Osman Sami, Koide Kazunori
机构信息
Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 15260.
出版信息
Tetrahedron Lett. 2008 Nov 10;49(46):6550-6552. doi: 10.1016/j.tetlet.2008.09.008.
Abstract
A new transformation between 2-pyridinecarboxyaldehyde and gamma-hydroxy-alpha,beta-acetylenic esters to form highly functionalized cyclic acetals was discovered. This transformation proceeds under very mild conditions without any additives and is promoted by the basic nature of the pyridine ring.
摘要
发现了一种2-吡啶甲醛与γ-羟基-α,β-炔酸酯之间形成高度官能化环状缩醛的新转化反应。该转化在非常温和的条件下进行，无需任何添加剂，且由吡啶环的碱性促进。
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