Department of Neurology, Philipps-University, Marburg 35039. Germany.
Mov Disord. 2010 Jan 15;25(1):13-27. doi: 10.1002/mds.22818.
Theory of mind (ToM), defined as the ability to infer other people's mental states, is a crucial prerequisite of human social interaction and a major topic of interest in the recent neuroscientific research. It has been proposed that ToM is mediated by a complex neuroanatomical network that includes the medial prefrontal cortex, the anterior gyrus cinguli, the sulcus temporalis superior, the temporal poles, and the amygdala. Various neurological and psychiatric diseases are accompanied by aspects of dysfunctional ToM processing. In this review, the association between basal ganglia, involved in the organization of complex cognitive and emotional behavior, and ToM processing is discussed. The purpose of this review is to provide an overview of research on ToM abilities in basal ganglia disorders, especially Parkinson's Disease and related disorders.
心理理论(Theory of mind,ToM),即推断他人心理状态的能力,是人类社会互动的关键前提,也是最近神经科学研究的主要课题。有人提出,ToM 是由一个复杂的神经解剖学网络介导的,该网络包括内侧前额叶皮质、前扣带回、颞上沟、颞极和杏仁核。各种神经和精神疾病都伴随着 ToM 处理功能失调的方面。在这篇综述中,讨论了基底神经节与参与复杂认知和情绪行为组织的关系,以及与 ToM 处理的关系。本文的目的是概述基底神经节障碍(特别是帕金森病和相关疾病)中的 ToM 能力研究。