Department of Clinical Neurology, Institute of Neurology, National Hospital for Neurology and Neurosurgery, 33 Queen Square, London, England.
Epilepsia. 1997 Nov;38(11 Suppl):S20-2. doi: 10.1111/j.1528-1157.1997.tb06118.x.
The exact mechanisms of sudden unexpected death in individuals with epilepsy (SUDEP) are unclear, and only an incomplete analysis of risk factors can be made. Clinical, epidemiologic, and electrophysiologic evidence suggests that most sudden deaths are related temporally to seizures, are unwitnessed, and that many occur during sleep. Individuals with generalized seizures, symptomatic epilepsy, severe or frequent seizures, and additional mental handicap or neurologic deficit are at greater risk, and the majority of cases probably occur in patients with chronic epilepsy. Young people are more at risk for SUDEP than older people with epilepsy, and risk factors in pediatric practice may differ from those in adult epileptology.
确切的癫痫患者猝死（SUDEP）的机制尚不清楚，并且只能对危险因素进行不完全的分析。临床，流行病学和电生理证据表明，大多数猝死与癫痫发作有时间关系，并且多数是无人目击的，并且很多发生在睡眠中。具有全身性发作，症状性癫痫，严重或频繁发作以及其他智力障碍或神经功能缺损的个体处于更大的风险中，大多数病例可能发生在慢性癫痫患者中。年轻人比患有癫痫的老年人更容易发生 SUDEP，儿科实践中的危险因素可能与成人癫痫学中的危险因素不同。
