Biem J, Hoffstein V
Department of Medicine, St. Michael's Hospital, University of Toronto, Ontario, Canada.
Am Rev Respir Dis. 1991 Feb;143(2):428-30. doi: 10.1164/ajrccm/143.2.428.
Pulmonary sarcoidosis in a young patient is usually a relatively benign disease that either resolves spontaneously or remains quiescent for many years. Very rarely it pursues a more aggressive course leading to progressive lung destruction. We report a young patient who presented with Stage III sarcoidosis and over a period of 4 yr progressed to severe cavitary disease with frequent superinfections leading to bronchiectasis and chronic suppuration of the lung, eventually requiring a pneumonectomy.
年轻患者的肺结节病通常是一种相对良性的疾病，要么自行缓解，要么多年保持静止状态。极罕见的情况下，它会呈更具侵袭性的病程，导致进行性肺破坏。我们报告一名患有Ⅲ期结节病的年轻患者，在4年的时间里病情进展为严重的空洞性疾病，频繁发生肺部感染，导致支气管扩张和肺慢性化脓，最终需要进行肺切除术。
