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可吸收生物材料与鼻腔填塞的进展

Advances in absorbable biomaterials and nasal packing.

作者信息

Valentine Rowan, Wormald Peter-John, Sindwani Raj

机构信息

Department of Surgery-Otorhinolaryngology, Head and Neck Surgery, The Queen Elizabeth Hospital, University of Adelaide, 28 Woodville Road, Woodville, Adelaide, SA 5011, Australia.

出版信息

Otolaryngol Clin North Am. 2009 Oct;42(5):813-28, ix. doi: 10.1016/j.otc.2009.07.009.

Abstract

Absorbable biomaterials are commonly used after endoscopic sinus surgery, both for hemostatic and wound healing considerations. Although removable nasal packing is the traditional method of controlling ongoing bleeding and modulating wound healing, it is uncomfortable for patients and associated with several complications. Currently available absorbable agents frequently incite an inflammatory reaction and have been shown in animal and human trials to adversely affect the wound healing process. Newer agents offer distinct advantages because of their unique composition and rapid clearance profiles. The selection of packing material used in any given sinus procedure should be based on surgeon preference and the details of the specific case.

摘要

出于止血和伤口愈合的考虑,可吸收生物材料在内镜鼻窦手术后常用。尽管可移除鼻腔填塞是控制持续出血和调节伤口愈合的传统方法,但它让患者不适且伴有多种并发症。目前可用的可吸收剂常常引发炎症反应,并且在动物和人体试验中已表明会对伤口愈合过程产生不利影响。新型可吸收剂因其独特的成分和快速清除特性而具有明显优势。在任何特定鼻窦手术中使用的填塞材料的选择应基于外科医生的偏好和具体病例的细节。

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