心肌血容量与心肌耗氧量相关：犬模型心脏磁共振的实验研究。
Myocardial blood volume is associated with myocardial oxygen consumption: an experimental study with cardiac magnetic resonance in a canine model.
机构信息
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA.
出版信息
JACC Cardiovasc Imaging. 2009 Nov;2(11):1313-20. doi: 10.1016/j.jcmg.2009.07.010.
Abstract
Understanding the oxygen consumption of the left ventricular myocardium provides important insight into the relationship between myocardial oxygen supply and demand. In other territories, cardiac magnetic resonance has been utilized to measure myocardial oxygen consumption with a blood level oxygen dependent (BOLD) technique. The BOLD technology requires repetitive sampling of stationary tissues and is frequently implemented in areas such as the brain. A limitation to utilizing BOLD cardiac magnetic resonance techniques in the heart has been cardiac motion. In this study, we document a methodology for acquiring BOLD images in the heart and demonstrate the utility of the technique for identifying associations between myocardial oxygen consumption and blood flow.
摘要
了解左心室心肌的耗氧量可以深入了解心肌氧供与氧需之间的关系。在其他领域，心脏磁共振已被用于通过血氧水平依赖（BOLD）技术来测量心肌耗氧量。BOLD 技术需要对静止组织进行重复采样，并且经常在大脑等区域实施。BOLD 心脏磁共振技术在心脏中的应用受到心脏运动的限制。在这项研究中，我们记录了一种在心脏中获取 BOLD 图像的方法，并证明了该技术在识别心肌耗氧量与血流之间的关联方面的效用。
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