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系统发育分析表明,猫免疫缺陷病毒A和B分支是独立传入中欧的,并鉴定出了B分支的多种变体。

Phylogenetic analysis suggests independent introduction of feline immunodeficiency virus clades A and B to Central Europe and identifies diverse variants of clade B.

作者信息

Steinrigl Adolf, Ertl Reinhard, Langbein Ines, Klein Dieter

机构信息

Institute of Virology, Department of Pathobiology, University of Veterinary Medicine, A-1210 Vienna, Austria.

出版信息

Vet Immunol Immunopathol. 2010 Mar 15;134(1-2):82-9. doi: 10.1016/j.vetimm.2009.10.013. Epub 2009 Oct 14.

Abstract

Phylogenetic analysis of European feline immunodeficiency virus sequences confirms a highly distinct pattern in the occurrence of FIV-subtypes within Germany and Austria, indicating little mixing and at least two independent introductions of FIV. There is also evidence for a North to South gradient of FIV subtype distribution in Europe, with subtype A being more common in the North, while subtype B is prevalent in the South of Europe. In addition, among Austrian subtype B sequences, considerable differences from classical subtype B sequences were detected by bootscanning, which either suggests recombination with so far unrecognized subtypes, or a long period of independent evolution.

摘要

对欧洲猫免疫缺陷病毒序列的系统发育分析证实,德国和奥地利境内猫免疫缺陷病毒亚型的出现呈现出高度独特的模式,这表明病毒混合极少,且猫免疫缺陷病毒至少有两次独立传入。还有证据表明,欧洲猫免疫缺陷病毒亚型分布存在从北到南的梯度变化,A亚型在北方更为常见,而B亚型在欧洲南部流行。此外,在奥地利的B亚型序列中,通过靴带扫描检测到与经典B亚型序列存在显著差异,这要么表明与迄今未识别的亚型发生了重组,要么表明经历了长时间的独立进化。

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