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脊膜内马尾椎管转移的肾细胞癌:病例报告及文献复习。

Intradural spinal metastasis to the cauda equina in renal cell carcinoma: a case report and review of the literature.

机构信息

Department of Neurosurgery, Dong Gwang Ju Woori Hospital, Gwangju, Korea.

出版信息

Spine (Phila Pa 1976). 2009 Nov 15;34(24):E892-5. doi: 10.1097/BRS.0b013e3181b34e6c.

DOI:10.1097/BRS.0b013e3181b34e6c
PMID:19910759
Abstract

STUDY DESIGN

Case description.

OBJECTIVES

To describe a case of intradural metastasis from a renal cell carcinoma (RCC) spread to the cauda equina, and review the pertinent medical literature.

SUMMARY OF BACKGROUND DATA

Intradural spinal metastasis is rare, accounting for 6% of all spinal metastases. Only 7 cases of intradural metastasis from a RCC to the cauda equina have been previously reported.

METHODS

A 41-year-old male presented with a 1-month history of severe back pain radiating to both legs. The patient underwent a right nephrectomy for treatment of a RCC 1-year before admission. Magnetic resonance imaging showed a well-demarcated, intradural extramedullary mass at the L2 vertebra.

RESULTS

After a total laminectomy, total excision of the tumor was achieved followed by rapid improvement of the back pain. The tumor was histologically verified as metastatic RCC, identical to that of a previous tumor specimen. The patient was asymptomatic on the 1-year follow-up.

CONCLUSION

Although the majority of cauda equina tumors are primary tumors, intradural metastasis should be considered before surgery in patients with previously treated RCC.

摘要

研究设计

病例描述。

目的

描述一例肾细胞癌(RCC)向马尾椎管内转移的病例,并复习相关医学文献。

背景资料概要

椎管内脊髓转移较为罕见,占所有脊髓转移的 6%。先前仅有 7 例 RCC 向马尾椎管内转移的病例报道。

方法

一名 41 岁男性,因严重背痛伴双下肢放射痛 1 个月就诊。患者 1 年前因 RCC 行右肾切除术。磁共振成像显示 L2 椎体水平有一界限清楚的硬脊膜外髓内肿块。

结果

行全椎板切除术,肿瘤全切除后,背痛迅速缓解。肿瘤的组织学证实为转移性 RCC,与之前的肿瘤标本相同。患者在 1 年随访时无症状。

结论

虽然大多数马尾肿瘤为原发性肿瘤,但对于有既往 RCC 治疗史的患者,在手术前应考虑硬脊膜内转移。

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