Montreal, Quebec, Canada From the Division of Plastic and Reconstructive Surgery, Department of Surgery, McGill University.
Plast Reconstr Surg. 2010 Jan;125(1):265-273. doi: 10.1097/PRS.0b013e3181c2a55a.
Infantile hemangiomas represent one of the most common childhood tumors. The authors have previously demonstrated that the most appropriate management for such tumors is a nonoperative approach. Some authors have recently advocated surgical management as the primary treatment. Medical treatment such as steroids or interferon therapy has also been proposed. Definitive treatment for infantile parotid gland hemangioma remains controversial.
In the retrospective study portion of this article, the authors reviewed the last 400 charts of children with hemangiomas managed at the Montreal Children's Hospital over the past 40 years. Twenty patients with parotid hemangiomas were identified. In the literature review portion, the Ovid MEDLINE and PubMed databases were used to retrieve all published original articles on the management of parotid hemangiomas from 1950 to December of 2008.
All of the authors' patients underwent successful nonoperative management, with 100 percent resolution of their parotid hemangiomas within 2 years of diagnosis, with an average follow-up time of 8.6 +/- 5.7 years. There were no complications of any of the treatments. The literature review retrieved a total of 413 patients in 12 original articles and four case reports. Management included observation and medical (steroid or interferon) and/or surgical treatment. Complications included failure to thrive, scarring, facial nerve palsy, and death.
The authors have shown that nonoperative therapy resulted in regression and involution of infantile parotid hemangiomas with no major complications.
婴儿血管瘤是最常见的儿童肿瘤之一。作者之前已经证明,此类肿瘤最合适的治疗方法是非手术方法。最近一些作者提倡将手术治疗作为主要治疗方法。也有作者提出采用医学治疗,如皮质类固醇或干扰素治疗。对于婴儿腮腺血管瘤的确定性治疗仍然存在争议。
在本文的回顾性研究部分,作者回顾了过去 40 年来在蒙特利尔儿童医院接受治疗的 400 例血管瘤患儿的最后 400 份图表。确定了 20 例腮腺血管瘤患者。在文献回顾部分,作者使用 Ovid MEDLINE 和 PubMed 数据库检索了从 1950 年至 2008 年 12 月期间发表的所有关于腮腺血管瘤治疗的原始文章。
所有作者的患者均成功接受非手术治疗,腮腺血管瘤在诊断后 2 年内完全消退,平均随访时间为 8.6 ± 5.7 年。所有治疗均无并发症。文献综述共检索到 12 篇原始文章和 4 篇病例报告中的 413 例患者。治疗方法包括观察、医学(皮质类固醇或干扰素)和/或手术治疗。并发症包括生长迟缓、瘢痕、面神经瘫痪和死亡。
作者表明,非手术治疗可使婴儿腮腺血管瘤消退和萎缩,且无严重并发症。