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延髓背侧血管母细胞瘤切除术后持续性高血压和心动过速:与神经原性血管运动中枢交感神经活性过度的关系。

Continuous hypertension and tachycardia after resection of a hemangioblastoma behind the dorsal medulla oblongata: relationship to sympathetic overactivity at the neurogenic vasomotor center.

机构信息

Department of Neurosurgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.

出版信息

J Neurosurg. 2010 Aug;113(2):369-73. doi: 10.3171/2009.10.JNS09504.

Abstract

A very rare case of continuous hypertension and tachycardia after excision of a cerebellar hemangioblastoma at the dorsal medulla oblongata is presented. This 21-year-old man was admitted to the authors' hospital with a headache and dizziness. Radiological examination revealed a tumor located behind the dorsal medulla oblongata and compressing it substantially. The tumor was completely resected, but after the surgery the patient experienced prolonged hypertension and tachycardia. Postoperative MR imaging showed a small injury at the dorsocaudal medulla that was located at the caudal site of the nucleus of the tractus solitarius (NTS). Because the NTS has been reported to play a central role in cardiovascular regulation along with the rostral ventrolateral medulla, the authors considered it possible that the NTS injury was the cause of the prolonged elevation of sympathetic tone.

摘要

本文报道了 1 例极为罕见的延髓背侧小脑血管瘤切除术后持续性高血压和心动过速病例。这名 21 岁男性因头痛和头晕被收入作者医院。影像学检查显示肿瘤位于延髓背侧,对其造成明显压迫。肿瘤被完全切除,但术后患者出现持续性高血压和心动过速。术后磁共振成像显示延髓背侧尾端有一小处损伤,位于孤束核(NTS)的尾端部位。由于 NTS 与延髓腹外侧前部一起在心血管调节中起核心作用,作者认为 NTS 损伤可能是交感神经张力持续升高的原因。

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