Advanced Lung Disease and Lung Transplant Unit, Royal Perth Hospital, Perth Western Australia, Australia.
Intern Med J. 2009 Nov;39(11):766-70. doi: 10.1111/j.1445-5994.2009.02051.x.
Pulmonary arterial hypertension (PAH) in pregnancy carries a mortality of 30-56%. There are few published data to guide clinicians in its management. Two pregnant women with severe PAH have been treated at Royal Perth Hospital with a successful result in both. Their presentation and management are described. We review the physiological changes in pregnancy, pathophysiology in PAH, and review the literature describing treatment of PAH in pregnancy.
妊娠合并肺动脉高压（PAH）的死亡率为 30-56%。目前，关于其管理的临床数据十分有限。西澳皇家医院成功治疗了两名患有严重 PAH 的孕妇，现将其临床表现和管理经验进行介绍。我们回顾了妊娠时的生理变化、PAH 的病理生理学，并对描述妊娠合并 PAH 治疗的文献进行了复习。
