疟原虫红细胞结合配体：细胞内转运与寄生虫毒力。
Erythrocyte binding ligands in malaria parasites: intracellular trafficking and parasite virulence.
机构信息
Department of Protozoology, Institute of Tropical Medicine and the Global Center of Excellence Program, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Japan.
出版信息
Acta Trop. 2010 Jun;114(3):131-7. doi: 10.1016/j.actatropica.2009.10.025. Epub 2009 Nov 11.
The intracellular trafficking of an Erythrocyte Binding Like (EBL) ligand has recently been shown to dramatically affect the multiplication rate and virulence of the rodent malaria parasite Plasmodium yoelii yoelii. In this review, we describe the current understanding of the role of EBL and other erythrocyte binding ligands in erythrocyte invasion, and discuss the mechanisms by which they may control multiplication rates and virulence in malaria parasites.
红细胞结合样（EBL）配体的细胞内运输最近被证明会极大地影响啮齿动物疟原虫 Plasmodium yoelii yoelii 的繁殖率和毒力。在这篇综述中，我们描述了目前对 EBL 和其他红细胞结合配体在红细胞入侵中的作用的理解，并讨论了它们可能控制疟原虫繁殖率和毒力的机制。
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