Department of Pediatrics, University of Verona, Verona, Italy.
J Pediatr. 2009 Dec;155(6):940-1. doi: 10.1016/j.jpeds.2009.05.033.
We describe a child who had anaphylactic hypersensitivity to imiglucerase therapy for Gaucher disease. Treatment was stopped and symptoms returned. After immune desensitization to imiglucerase using a rush protocol, the patient was able to resume treatment and has not had further hypersensitivity complications to date.
我们描述了一名患有戈谢病的儿童对伊米苷酶治疗产生过敏反应。停止治疗后症状复发。通过 rush 方案进行伊米苷酶免疫脱敏后,该患者能够恢复治疗,迄今为止未再发生过敏反应并发症。