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免疫功能正常宿主的鼻孢子菌感染

[Scedosporium apiospermum rhinosinusal infection in an immunocompetent host].

作者信息

Chanqueo Leonardo, Gutiérrez Catalina, Tapia Cecilia, Silva Víctor, Razeto Leopoldo, Misad Carlos

机构信息

Unidad de Infectología, Servicio de Medicina Interna, Hospital San Juan de Dios, Santiago, Chile.

出版信息

Rev Chilena Infectol. 2009 Oct;26(5):453-6. Epub 2009 Nov 9.

Abstract

Scedosporium species can cause colonization, superficial and deep localized infection or systemic disease, especially in immunocompromised hosts. We report a case of localized infection due to Scedosporium apiospermum in a 47 year old woman, with previous nasal surgery. She consulted for recurrent mucopurulent post-nasal discharge not responding to antibiotics. Computed tomography showed opacification of right maxillary sinus. Surgery was performed to removed abnormal tissue from sinus; biopsy revealed chronic sinusitis with aggregate of tightly packed hyphae suggestive of filamentous fungi. The microbiology fungal culture reported Scedosporium apiospermum.

摘要

波氏假阿利什霉属菌种可引起定植、浅表和深部局限性感染或全身性疾病,尤其是在免疫功能低下的宿主中。我们报告一例47岁曾接受鼻部手术的女性因阿利什霉引起的局限性感染病例。她因抗生素治疗无效的反复鼻后黏液脓性分泌物前来就诊。计算机断层扫描显示右上颌窦混浊。进行了手术以清除鼻窦中的异常组织;活检显示为慢性鼻窦炎,有紧密堆积的菌丝团,提示丝状真菌。微生物真菌培养报告为阿利什霉。

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