Department of Diagnostic and Therapeutic Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon-city, Ehime, 791-0295, Japan.
Eur Radiol. 2010 May;20(5):1139-48. doi: 10.1007/s00330-009-1657-2. Epub 2009 Nov 14.
To determine LV function at different distances from myocardial infarction (MI) by using 3-T tagged MRI and late gadolinium enhancement (LGE).
Cardiac MR images were acquired from 21 patients with previous MI. The harmonic phase (HARP) method was used to calculate radial and circumferential strain (RS, CS). The two strains were synchronised by subtracting the CS from the RS at the same time, and this was defined as the efficient strain (ES). Peak strain (P-RS, P-CS, P-ES) and time to peak strain (T-RS, T-CS, T-ES) were used as estimates of contractile function. Based on the presence of LGE, myocardium was classified into infarct, border zone, adjacent and remote areas.
P-RS and P-ES were significantly greater for remote than for adjacent and infarct areas. P-CS values were significantly greater for remote and border zone than for infarct areas. T-RS and T-ES were significantly shorter for remote and border zone than for infarct areas. T-CS was significantly shorter for border zone than for infarct areas.
Contractile dysfunction demonstrated by peak strain was correlated with location at different distances from the infarct. In the border zone, contractile deformation was characterised as earlier T-RS, T-CS and T-ES and greater P-CS than in the infarct area.
利用 3-T 标记 MRI 和钆延迟增强（LGE）技术，确定不同距离心肌梗死（MI）的左心室（LV）功能。
对 21 例有既往 MI 的患者进行心脏 MRI 采集。采用谐波相位（HARP）法计算径向和周向应变（RS、CS）。通过从 RS 中减去 CS，将两种应变同步，并将其定义为有效应变（ES）。采用峰值应变（P-RS、P-CS、P-ES）和应变达峰时间（T-RS、T-CS、T-ES）作为收缩功能的指标。根据 LGE 的存在，将心肌分为梗死区、边缘区、相邻区和远隔区。
与梗死区和相邻区相比，远隔区的 P-RS 和 P-ES 明显更大。与梗死区相比，远隔区和边缘区的 P-CS 值明显更大。与梗死区相比，远隔区和边缘区的 T-RS 和 T-ES 明显缩短。与梗死区相比，边缘区的 T-CS 明显缩短。
与梗死部位的距离不同，峰值应变显示的收缩功能障碍与部位相关。在边缘区，收缩变形的特点是 T-RS、T-CS 和 T-ES 更早，P-CS 大于梗死区。
