Chopra P, Narula J P, Tandon R
Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
Int J Cardiol. 1991 Jan;30(1):124-7. doi: 10.1016/0167-5273(91)90136-d.
Electron microscopic evaluation of subcutaneous nodules excised from two cases of acute rheumatic fever showed an electron dense and smudgy material which had a distinct filamentous appearance in places. The latter was recognized as collagen. This corresponded to the fibrinoid necrosis seen under the light microscope. In addition, several histiomonocytic cells and fibroblasts were seen. A large number of cells were degenerated. A fair degree of resemblance of the nodule both by light and electron microscopy to the rheumatoid nodule was noted.
对两例急性风湿热患者切除的皮下结节进行电子显微镜评估，结果显示有一种电子密度高且模糊的物质，在某些部位呈现出明显的丝状外观。后者被确认为胶原蛋白。这与光镜下所见的纤维蛋白样坏死相对应。此外，可见数个组织单核细胞和成纤维细胞。大量细胞发生变性。通过光镜和电子显微镜观察发现，该结节与类风湿结节有相当程度的相似性。
