通过 1D 和 2D NMR 光谱学确定来自欧洲李的新 C-烷基化类黄酮李苷 A 和 B 的结构。

Structural determination of prunusins A and B, new C-alkylated flavonoids from Prunus domestica, by 1D and 2D NMR spectroscopy.

机构信息

PNEC National University of Sciences and Technology, Karachi-75270, Pakistan.

出版信息

Magn Reson Chem. 2010 Feb;48(2):151-4. doi: 10.1002/mrc.2540.

PMID:19918802

Abstract

Prunusins A (1) and B (2), the new C-alkylated flavonoids, have been isolated from the seed kernels of Prunus domestica. Their structures were assigned from (1)H and (13)C nuclear magnetic resonating spectra, DEPT and by correlation spectroscopy, HMQC and HMBC experiments. 3, 5, 7, 4'-Tetrahydroxyflavone (3) and 3, 5, 7-trihydroxy-8, 4'-dimethoxyflavone (4) have also been reported from this species. Both compounds (1) and (2) showed significant antifungal activity against pathogenic fungus Trichophyton simmi.

摘要

Prunusins A (1) 和 B (2)，两种新的 C-烷基化黄酮类化合物，已从桃的种仁中分离得到。它们的结构是根据 (1)H 和 (13)C 核磁共振谱、DEPT 和相关光谱、HMQC 和 HMBC 实验确定的。3,5,7,4'-四羟基黄酮 (3) 和 3,5,7-三羟基-8,4'-二甲氧基黄酮 (4) 也已从该种植物中报道。化合物 (1) 和 (2) 均对致病真菌须癣毛癣菌表现出显著的抗真菌活性。