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Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products.

作者信息

Carpenter John F, Randolph Theodore W, Jiskoot Wim, Crommelin Daan J A, Middaugh C Russell, Winter Gerhard

机构信息

Department of Pharmaceutical Sciences, Center for Pharmaceutical Biotechnology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado 80045, USA.

出版信息

J Pharm Sci. 2010 May;99(5):2200-8. doi: 10.1002/jps.21989.

DOI:10.1002/jps.21989
PMID:19918982
Abstract
摘要

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