State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
Org Lett. 2009 Dec 17;11(24):5694-7. doi: 10.1021/ol9024474.
The total synthesis of four possible isomers with the proposed structure of antimycobacterial depsipeptide lydiamycin B is achieved. None of them shows identical NMR data with those reported for natural lydiamycin B, indicating that further structural revisions are required.
四种可能的立体异构体与具有抗分枝杆菌环二肽利迪链菌素 B 结构的提议结构的全合成已完成。它们都没有显示出与天然利迪链菌素 B 报道的数据相同的 NMR 数据，表明需要进一步的结构修订。
