Division of Urology, University of Missouri, MO, USA.
Clin Transplant. 2010 May-Jun;24(3):429-32. doi: 10.1111/j.1399-0012.2009.01153.x. Epub 2009 Nov 16.
Laparoscopy is a standard surgical option for live donor nephrectomy (LDN) at the majority of transplant centers. Equivalent graft survival with shorter convalescence has been reported by several large volume centers. With the arrival of an experienced laparoscopic surgeon in 2002, we began to offer laparoscopic LDN at our institution. We report our experience as a large volume laparoscopic surgery program but a low volume transplant center.
A retrospective review of the previous 34 LDN (17 open, 17 laparoscopic) performed at the University of Missouri were included. A single laparoscopic surgeon performed all laparoscopic procedures. Hand assisted laparoscopy was performed in 15 and standard laparoscopy with a pfannenstiel incision in two. Open procedures were performed through anterior subcostal or flank incision. A single surgeon performed all open procedures.
There was no statistical difference in age, body mass index or American Society of Anesthesiologies Score between the two groups. Mean operative time, estimated blood loss and hospital stay were 229 minutes, 324 cc and 2.2 days respectively in the laparoscopic group compared to 202 minutes, 440 cc and five days for the open group. Average warm ischemia time was 179 seconds. Recipient creatinine for the two groups at one week, one month and one year was not statistically significantly different. Each group had one graft loss due to medication noncompliance.
For small transplant centers with an advanced laparoscopic program, laparoscopic LDN is a safe procedure with comparable outcomes to major transplant centers.
腹腔镜手术是大多数移植中心活体供肾切除术(LDN)的标准手术选择。几个大容量中心报告了恢复期更短但移植效果相当的结果。自 2002 年一位经验丰富的腹腔镜外科医生加入以来,我们开始在我们的机构提供腹腔镜 LDN。我们报告了我们作为一个大容量腹腔镜手术计划但低容量移植中心的经验。
回顾了密苏里大学之前进行的 34 例 LDN(17 例开放手术,17 例腹腔镜手术)。一位经验丰富的腹腔镜外科医生进行了所有的腹腔镜手术。15 例采用手助腹腔镜,2 例采用标准腹腔镜和 Pfannenstiel 切口。开放手术通过前肋下或侧肋切口进行。所有开放手术均由一位外科医生完成。
两组在年龄、体重指数或美国麻醉医师协会评分方面无统计学差异。腹腔镜组的平均手术时间、估计失血量和住院时间分别为 229 分钟、324 毫升和 2.2 天,而开放组分别为 202 分钟、440 毫升和 5 天。平均热缺血时间为 179 秒。两组受者术后一周、一个月和一年的肌酐值无统计学差异。两组均有一例因药物不遵医嘱导致移植物丢失。
对于具有先进腹腔镜计划的小型移植中心,腹腔镜 LDN 是一种安全的手术,其结果与主要移植中心相当。